Substance
ID:387723
Names and Identifiers
IUPAC name
8-hydroxy-2-methyl-3,4-dihydroquinazolin-4-one
IUPAC Traditional name
8-hydroxy-2-methyl-3H-quinazolin-4-one
Synonyms
NSC 6968078-Hydroxy-2-methyl-4(3H)-quinazolinone
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Methanol
Ethanol
Ethyl Acetate
Apperance
Off-White to Pale Yellow Solid
Melting Point
>250°C (dec.)
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Product Information
Certificate of Analysis
Molecule Details
A potent inhibitor of poly (ADP-ribose) polymerase (PARP). Ki and IC50 values are 48 and 400 nM respectively.
Molecular Spectra
No Data Available
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References
• Griffin, R.J., et al.: J. Med. Chem., 41, 5247 (1998)
• De Soto, J., et al.: Int. J. Biol. Sci., 2, 179 (1998)