Substance
ID:386572
(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester
Names and Identifiers
IUPAC name
1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
IUPAC Traditional name
1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
Synonyms
N-tert-Butoxycarbonyl-L-hydroxyproline Methyl EsterMethyl (4R)-N-Boc-4-hydroxy-L-prolinate(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester(2S,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylic Acid 1-(1,1-Dimethylethyl) 2-Methyl Ester1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-dimethylethyl) 2-methyl ester, (2S-trans)-1-tert-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic Acid Methyl Ester(2S,4R)-1-Boc-4-hydroxy-L-proline Methyl Ester
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Physical Property
Solubility
DMF
Ethyl Acetate
Chloroform
Dichloromethane
Apperance
Clear Colourless Oil
Safety Information
MSDS Link
Molecule Details
(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.
Molecular Spectra
No Data Available
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References
• Freer, R., et al.: Biochemistry, 21, 257 (1982)
• Cavicchioni, G., et al.; Bioorg. Chem., 34, 298 (1982)
• Selvatici, R., et al.: Eur. J. Pharmacol., 534, 1 (1982)
• Higgins, J., et al.: J. Med. Chem., 39, 1013 (1982)