Substance
ID:384811
Names and Identifiers
Synonyms
Etoposidetrans-EtoposideVepesid(5R,5aR,8aR,9S)-9-[[4,6-O-(1R)-Ethylidene-β-D-glucopyranosyl]oxy]-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-oneVepesid JZuyeyidalP 16-213EPEG
IUPAC Traditional name
etoposide
IUPAC name
(10R,11R,15R,16S)-16-{[(2R,4aR,6R,7R,8R,8aS)-7,8-dihydroxy-2-methyl-hexahydro-2H-pyrano[3,2-d][1,3]dioxin-6-yl]oxy}-10-(4-hydroxy-3,5-dimethoxyphenyl)-4,6,13-trioxatetracyclo[7.7.0.03,7.011,15]hexadeca-1(9),2,7-trien-12-one
Registration numbers
CAS Number
Properties
Physical Property
Apperance
White Solid
Solubility
Methanol
Melting Point
254-256°C
Safety Information
MSDS Link
Storage Condition
-20°C Freezer, Under Inert Atmosphere
Product Information
Certificate of Analysis
Molecule Details
A DNA topoisomerase II inhibitor. Semi-synthetic derivative of podophyllotoxin, related structurally to Teniposide. Antineoplastic.
Molecular Spectra
No Data Available
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References
• Burden, D.A., et al.: J. Biol. Chem., 271, 29238 (1996)
• Joel, S., et al.: Cancer Treat. Rev., 22, 179 (1996)