Substance
ID:384311
Names and Identifiers
IUPAC Traditional name
N-ethylmaleimide
IUPAC name
1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione
Synonyms
NEMEthylmaleimideN-Ethyl MaleimideMaleic Acid N-EthylimideNSC 76381-Ethyl-1H-pyrrole-2,5-dione
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Molecule Details
Reagent for the covalent modification of cysteine residues in proteins.NEM gives a clear solution in ethanol at 50 mg/ml. NEM dissolves in water (>50 mg in 4 ml); however, aqueous solutions are unstable. The rate of hydrolysis is pseudo-first order and si
Molecular Spectra
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References
• Sheehan, M., et al.: J. Cell Biol., 106, 1 (1988)
• Vogel, K., et al.: J. Biol. Chem., 275, 2959 (1988)
• Ramos, C., et al.: Biochem. J., 400, 393 (1988)