Substance
ID:384049
Names and Identifiers
IUPAC Traditional name
entinostat
IUPAC name
pyridin-3-ylmethyl N-({4-[(2-aminophenyl)carbamoyl]phenyl}methyl)carbamate
Synonyms
Entinostat(Pyridin-3-yl)methyl 4-(2-Aminophenylcarbamoyl)benzylcarbamateMS 275MS 275-27MS 27-275N-(2-Aminophenyl)-4-[N-(pyridine-3-yl-methoxycarbonyl)-aminomethyl]benzamideSNDX 275N-[[4-[[(2-Aminophenyl)amino]carbonyl]phenyl]methyl]carbamic Acid 3-Pyridinylmethyl Ester
Registration numbers
CAS Number
Properties
Physical Property
Melting Point
158-160°C
Solubility
Methanol
DMSO
Apperance
Yellow Solid
Safety Information
MSDS Link
Storage Condition
Refrigerator
Product Information
Certificate of Analysis
Molecule Details
Entinostat is an emerging HDACi (histone deacetylase inhibitor). Entinostat is used for treatment of solid tumors and hematologic malignancies.
Molecular Spectra
No Data Available
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References
• Maggio, S., et al.: Cancer Res., 64, 2590 (2003)
• Hu, E., et al.: J. Pharmacol. Exp. Ther., 307, 720 (2003)
• Gojo, I., et al.: Blood, 109, 2781 (2003)
• Xu, W; Oncogene, 26, 5541 (2003)