Substance
ID:383965
Names and Identifiers
IUPAC Traditional name
vaniqa hydrate hydrochloride
IUPAC name
2,5-diamino-2-(difluoromethyl)pentanoic acid hydrate hydrochloride
Synonyms
DFMODL-2-(Difluoromethyl)ornithineα,δ-Diamino-α-(difluoromethyl)valeric Acidα-(Difluoromethyl)-DL-ornithineα-(Difluoromethyl)ornithineElfornithine2-(Difluoromethyl)ornithineDL-α-(Difluoromethyl)ornithineMDL 71782AOrnidylRFI 71782RMI 717822-(Difluoromethyl)-DL-ornithine Hydrochloride HydrateMDL 71782Eflornithine Hydrochloride Monohydrate
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Water
Apperance
White Solid
Melting Point
>210°C (dec.)
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Molecule Details
Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.
Molecular Spectra
No Data Available
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References
• Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1980)
• Bacchi, C.J., et al.: Science, 210, 332 (1980)
• Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1980)