Substance
ID:383934
Names and Identifiers
Synonyms
EntacaponeOR-611ComtanComtess(2E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethyl-2-propenamide
IUPAC Traditional name
entacapone
IUPAC name
(2E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Chloroform
Methanol
Apperance
Yellow Solid
Melting Point
162-163°C
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
(E)-Isomer of Entacapone polymorphic form A. Peripherally acting inhibitor of catechol-O-methyl transferase (COMT), an enzyme involved in the metabolism of catecholamine neurotransmitters and related drugs. Antiparkinsonian.
Molecular Spectra
No Data Available
Click here to submit data
References
• Wikberg, T., et al.: Eur. J. Drug Metab. Pharmacokinet., 18, 359 (1992)
• Karlsson, M., et al.: J. Pharm. Biomed. Anal., 10, 593 (1992)
• Nissinen, E., et al.: Arch. Pharmacol., 346, 262 (1992)