Substance

ID:381715

N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride

Names and Identifiers
Synonyms
11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine, Dihydrochloride, DBTP,N-Des[2-(2-hydroxyethoxy)ethyl] Quetiapine Dihydrochloride
IUPAC Traditional name
10-(piperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
IUPAC name
10-(piperazin-1-yl)-2-thia-9-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaene
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Methanol
DMSO
Melting Point
287-292°C
Apperance
Off-White to Pale-Yellow Solid
Product Information
Certificate of Analysis
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Molecule Details
A metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic.
Molecular Spectra
No Data Available
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References
• DeVane, C., et al.: Clin. Pharmacokinet., 40, 509 (2001)
• Lin, S., et al.: J. Anal. Toxicol., 28, 443 (2001)
• Zhou, S., et al.: Curr. Drug Metab., 5, 415 (2001)
• Grimm, S., et al.: Br. J. Clin. Pharmacol., 61, 58 (2001)