Substance

ID:380928

Names and Identifiers
IUPAC name
N-(2-chloro-6-methylphenyl)-2-({6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl}amino)-1,3-thiazole-5-carboxamide
Synonyms
DasatinibBMS-354825N-[2-Chloro-6-methylphenyl]-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl]-2-methyl-4-pyrimidinyl]amino]-5-thiazolecarboxamide
IUPAC Traditional name
dasatinib
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Physical Property
Melting Point
275-286°C
Solubility
Methanol
DMSO
Apperance
White to Off-White Solid
Molecule Details
A new, oral, small-molecule Tyrosine Kinase Inhibitor (TKI) for the treatment of CML. Antineoplastic.
Molecular Spectra
No Data Available
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References
• Lombardo, L.J., et al: J. Med. Chem., 47, 6658 (2004)
• Shah, N. P., et al.: Science, 305, 399 (2004)
• O’Hare, T., et al.: Curr. Opin. Genet. Dev., 16, 92 (2004)