Substance
ID:380293
Names and Identifiers
IUPAC Traditional name
tofacitinib
IUPAC name
3-[(3R,4R)-4-methyl-3-[methyl({7H-pyrrolo[2,3-d]pyrimidin-4-yl})amino]piperidin-1-yl]-3-oxopropanenitrile
Synonyms
TofacitinibCP-6905501-(Cyanoacetyl)-4-methyl-N-methyl-N-1H-pyrrolo[2,3-d]pyrimidin-4-yl-3-piperidinamine(3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-β-oxo-1-piperidinepropanenitrileCP 690550
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Physical Property
Melting Point
115-117°C
Solubility
Methanol
DMSO
Chloroform
Apperance
Light Pink to Pale Orange Solid
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Molecule Details
CP-690550 is a pyrrolo[2,3-d]pyrimidine derivative, as Janus kinase inhibitor for treatment of rheumatoid arthritis.
Molecular Spectra
No Data Available
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References
• Hutmacher, M., et al.:
• Dayneka, N., et al.: J. Pharmacokin. Biopharm., 21, 457 (1979)
• Changelian, P., et al.: Science, 302, 875 (1979)
• Sheiner, L., et al.: Clin. Pharmacol. Ther., 25, 358 (1979)
• Lee, H., et al.: Clin. Pharmacol. Ther., 73, 348 (1979)