Substance
ID:380256
Names and Identifiers
IUPAC name
4-{6-chloro-2,9-diazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-10-yl}-1-methylpiperazin-1-ium-1-olate
Synonyms
8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine N-OxideClozapine N-Oxide
IUPAC Traditional name
4-{6-chloro-2,9-diazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,9,12,14-heptaen-10-yl}-1-methylpiperazin-1-ium-1-olate
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Ether
Acetone
Melting Point
255-260°C (dec.)
Apperance
Yellow Solid
Safety Information
Storage Condition
-20°C Freezer, Under Inert Atmosphere
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A 5-HT2 antagonist. A major metabolite of clozapine that can be monitored by HPLC. Possesses little or no activity towards serotonin receptors.
Molecular Spectra
No Data Available
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References
• Lin, G., et al.: J. Pharm. Sci, 83, 1412 (1994, Roth, B.L., et al.: J. Pharmacol. Exp. Ther., 268, 1403 (1994)