Substance
ID:380010
Names and Identifiers
IUPAC Traditional name
cidofovir
IUPAC name
({[(2S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid
Synonyms
[[(1S)-2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic Acid Hydrate(S)-1-(3-hydroxy-2-phosphonomethoxypropyl)cytosine HydrateGS 0504 HydrateVistide HydrateCidovir Hydrate(S)-[[2-(4-Amino-2-oxo-1(2H)-pyrimidinyl)-1-(hydroxymethyl)ethoxy]methyl]phosphonic Acid Hydrate(S)-HPMPC HydrateCidofovir Hydrate1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine Hydrate
Registration numbers
No Data Available
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Properties
Physical Property
Apperance
White Solid
Melting Point
256-260°C (dec.)
Solubility
DMSO (Sparingly)
Water (Sparingly)
Safety Information
Storage Condition
Refrigerator
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
An injectable antiviral medication for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It suppresses CMV replication by selective inhibition of viral DNA polymerase and therefore prevention of viral replication and transcription. I
Molecular Spectra
No Data Available
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References
• Ho, H.T. et al.: Mol. Pharmacol., 41, 197 (1996)
• Rahal, F.M. et al.: Ann. Internal Med., 125, 98 (1996)
• Johnson, J.A. et al.: Antimicrob. Agents Chemother., 43, 1190 (1996)