Substance
ID:378947
Names and Identifiers
IUPAC Traditional name
cetirizine
IUPAC name
2-(2-{4-[(4-chlorophenyl)(phenyl)methyl]piperazin-1-yl}ethoxy)acetic acid
Synonyms
SelitexTrizVirlixZirtinZyrtecZyrzineCetrizetRiztecZeranCetirizine Dihydrochloride[2-[4-[(4-Chlorophenyl)phenylmethyl]-1-piperazinyl]ethoxy]acetic Acid DihydrochlorideFormistinHistazine-1ZirtecCetrineCistamineEpirizineRyzenTomazineUCB-P 071SancotecZirtekZyrlexAlerlisinCetrakCestaCetirizHistazineNoseminP 071ReactineAlercetAlerid
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Water
Methanol
Apperance
White Solid
Melting Point
212-214°C
Safety Information
MSDS Link
Storage Condition
-20°C Freezer, Under Inert Atmosphere
Product Information
Certificate of Analysis
Molecule Details
A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.
Molecular Spectra
No Data Available
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References
• Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987)
• Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)
• De Vos, C., et al.: Ann. Allergy, 59, 278 (1987)
• Fadel, R., et al.: Clin. Allergy, 17, 373 (1987)