Substance
ID:378911
Names and Identifiers
IUPAC Traditional name
C2-ceramide
IUPAC name
N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]acetamide
Synonyms
N-Acetyl-D-sphingosineAcetyl CeramideN-AcetylsphingosineN-[(1S,2R,3E)-2-Hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]acetamideC2 Ceramide
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Dichloromethane
Chloroform
Melting Point
87-89°C
Apperance
White Solid
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Molecule Details
A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2.
Molecular Spectra
No Data Available
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References
• Inoue, T., et al.: J. Biol. Chem., 284, 9566 (2009)
• Rath, G., et al.: Int. J. Biochem. Cell Biol., 41, 1165 (2009)
• Kang, J., et al.: Bioorg. Med. Chem., 17, 1498 (2009)