Substance
ID:378701
Names and Identifiers
IUPAC name
1,3-bis(2-chloroethyl)-1-nitrosourea
IUPAC Traditional name
1,3-bis(2-chloroethyl)-1-nitrosourea
Synonyms
CarmustineBCNU, N,N’-Bis(2-chloroethyl)-N-nitrosourea, NSC-409962, Becenun, Bicnu,
Registration numbers
CAS Number
Properties
Product Information
Certificate of Analysis
Physical Property
Melting Point
30-32°C
Solubility
DMSO
Methanol
Apperance
Light Yellow to Pale Orange Solid
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Molecule Details
An alkylating and carbamoylating nitrosourea compound. It interacts with DNA, RNA and proteins causing DNA interstrand cross linking which is cytotoxic and leads to apoptotic cell death.
Molecular Spectra
No Data Available
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References
• Stahl, et al.: Chem. Res. Toxicol., 5, 106 (1992)
• Hickman, M.J., et al.: Proc. Natl. Acad. Sci. USA, 96(1992)
• 3676 (1992)
• 10764 (1992)
• Kokkinakis, D.M., et al.: Clin. Cancer Res., 5(1992)