Substance
ID:377171
Names and Identifiers
IUPAC Traditional name
(2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-ol
IUPAC name
(2R)-1-({4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl}oxy)propan-2-ol
Synonyms
L-Alanine (1R)-2-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]oxy]-1-methylethyl EsterBMS 582664Brivanib Alaninate
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A novel prodrug of dual vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1 kinase inhibitor. Antitumor agent.
Molecular Spectra
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References
• Ellis, L., et al.: Eur. J. Cancer, 32A, 2451 (1996)
• Bhide, R., et al.: J. Med. Chem., 49, 2143 (1996)
• Klagsbrun, M., et al.: Chem. Biol., 6, R217 (1996)
• Auguste, P., et al.: Cancer Res., 61, 1717 (1996)