Substance
ID:377043
Names and Identifiers
IUPAC name
(2R)-2-{[(tert-butoxy)carbonyl]amino}-5-(3-nitrocarbamimidamido)pentanoic acid
IUPAC Traditional name
(2R)-2-[(tert-butoxycarbonyl)amino]-5-(3-nitrocarbamimidamido)pentanoic acid
Synonyms
Nα-Boc-Nω-nitro-D-arginineN2-[(1,1-Dimethylethoxy)carbonyl]-N5-[imino(nitroamino)methyl]-D-ornithineNa-Boc-Nw-nitro-D-arginineBoc-D-Arg(NO2)-OH
Registration numbers
CAS Number
Properties
Safety Information
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Product Information
Certificate of Analysis
Molecule Details
Nα-Boc-Nω-nitro-D-arginine is used in the synthesis of selective inactivators of human plasma kallikrein via chloromethyl ketone formation. Nα-Boc-Nω-nitro-D-arginine also produced modest inhibition of the effects acetylcholine in rabbit aorta.
Molecular Spectra
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References
• Kettner, C. et al.: Biochemistry, 17, 4778 (1978)
• Moore, P.K. et al.: Br. J. Pharmacol., 99, 408 (1978)