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Substance
ID:376332
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Functional Group
Text
ID:192
Bexarotene
Toronto Research Chemicals
ID: B336750
Names and Identifiers
Synonyms
Bexarotene
LG 100069
LG 1069
LGD 1069
RO 26-4455
SR 11247
Targretin
Targretyn
Targrexin
4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic Acid
LG 69
Targret
IUPAC name
4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid
IUPAC Traditional name
bexarotene
Registration numbers
CAS Number
153559-49-0
Properties
Physical Property
Apperance
White Solid
Solubility
Chloroform
Methanol
Melting Point
230-231°C
Safety Information
MSDS Link
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Storage Condition
-20°C Freezer
Product Information
Certificate of Analysis
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Molecule Details
Used as an antineoplastic. A selective retinoid X receptor (RXR) agonist.
Molecular Spectra
No Data Available
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References
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Mukherjee, R., et al.: Nature, 386, 407 (1994)
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Gottardis, M.M., et al.: Cancer Res., 56, 5566 (1994)
•
Miller, V.A., et al.: J. Clin. Oncol., 15, 790 (1997)
•
Boehm, M.F., et al.: J. Med. Che., 37,2930 (1994)
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