Substance
ID:375284
Names and Identifiers
IUPAC name
4,7,11-trioxa-16-azatetracyclo[8.7.0.03,8.012,16]heptadeca-1,3(8),9-trien-17-one
IUPAC Traditional name
4,7,11-trioxa-16-azatetracyclo[8.7.0.03,8.012,16]heptadeca-1,3(8),9-trien-17-one
Synonyms
2,3,6a,7,8,9-Hexahydro-11H-1,4-dioxino[2,3-g]pyrrolo[2,1-b][1,3]benzoxazin-11-oneLiD 37BDP 37CX 614
Registration numbers
CAS Number
Properties
Physical Property
Apperance
White to Off-White Solid
Solubility
Chloroform
DMSO
Methanol
Melting Point
149-151°C
Safety Information
Storage Condition
Refrigerator
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
It is one of a series of AMPA modulators for the potential treatment of Alzheimer's disease, schizophrenia, and mild cognitive impairment (MCI). An ampakine drug that facilitates activation of glutamatergic AMPA receptors.
Molecular Spectra
No Data Available
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References
• Marini, A., et al.: J. Biol. Chem., 273, 29394 (1996)
• Balkowiec, A., et al.: J. Neurosci., 22, 10399 (1996)
• Dicou, E., et al.: Brain Res., 970, 221 (1996)
• Arai, A., et al.: J. Pharmacol. Exp. Ther., 278, 627 (1996)