Substance
ID:374157
Names and Identifiers
IUPAC Traditional name
[4-amino-2-(methylsulfanyl)pyrimidin-5-yl]methanol
IUPAC name
[4-amino-2-(methylsulfanyl)pyrimidin-5-yl]methanol
Synonyms
4-Amino-2-(methylthio)pyrimidine-5-carboxaldehyde4-Amino-2-(methylthio)-5-pyrimidinecarboxaldehyde4-Amino-2-methylsulfanylpyrimidine-5-carboxaldehydeNSC 165376
Registration numbers
CAS Number
Properties
Safety Information
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
Used for the preparation of pyridopyrimidines and naphthyridines as inhibitors of Akt kinase for the treatment of cancer.
Molecular Spectra
No Data Available
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References
• Zhao, Z., et al.: Bioorg. Med. Chem. Lett., 18, 49 (2001)
• Zinda, M., et al.: Clin. Cancer Res., 7, 2475 (2001)
• Breitenlechner, C., et al.: J. Med. Chem., 47, 1375 (2001)