Substance
ID:373942
(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid Hydrobromide
Names and Identifiers
IUPAC name
2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid hydrobromide
IUPAC Traditional name
AMPA hydrobromide
Synonyms
γ-Amino-3-hydroxy-5-methylisoxazole-4-propionic Αcid Hydrobromide(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid HydrobromideAMPAD,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Hydrobromide
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Water
Methanol
Melting Point
205-208°C
Apperance
White to Off-White Solid
Safety Information
MSDS Link
Storage Condition
-20°C Freezer
Product Information
Certificate of Analysis
Molecule Details
A potent and selective agonist of the excitatory neurotransmitter L-glutamic Acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists.
Molecular Spectra
No Data Available
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References
• Honore, T., et al.: J. Neurochem., 38, 173 (1980)
• MacDonald, J.F., et al.: Science, 253, 1132 (1991)
• Krogsgaard-Larsen, et al.: Nature, 284, 64 (1980)