Substance
ID:373940
Names and Identifiers
IUPAC name
2-amino-3-(3-hydroxy-5-methyl-1,2-oxazol-4-yl)propanoic acid
Synonyms
AMPAD,L-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acidγ-Amino-3-hydroxy-5-methylisoxazole-4-propionic Αcid(R,S)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid
IUPAC Traditional name
AMPA
Registration numbers
CAS Number
Properties
Physical Property
Melting Point
>200°C (dec.)
Apperance
White to Off-White Solid
Solubility
Water
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
A potent and selective agonist of the putative, excitatory neurotransmitter L-glutamic acid. AMPA does not interfere with binding sites for kainic acid in vitro, and AMPA- induced neuronal excitation is not significantly affected by NMDA antagonists.
Molecular Spectra
No Data Available
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References
• MacDonald, J.F., et al.: Science, 253, 1132 (1991)
• Krogsgaard-Larsen, et al.: Nature, 284, 64 (1980)
• Honore, T., et al.: J. Neurochem., 38, 173 (1980)