Substance
ID:373185
Names and Identifiers
IUPAC name
(2S,4S,5S,7S)-5-amino-N-(2-carbamoyl-2,2-dimethylethyl)-4-hydroxy-7-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-8-methyl-2-(propan-2-yl)nonanamide
Synonyms
SPP 100CGP60536BRasilez HemifumarateCGP 60536Tekturna Hemifumarate(αS,γS,δS,zS)-δ-Amino-N-(3-amino-2,2-dimethyl-3-oxopropyl)-γ-hydroxy-4-methoxy-3-(3-methoxypropoxy)-α,z-bis(1-methylethyl)benzeneoctanamide HemifumarateAliskiren Hemifumarate
IUPAC Traditional name
aliskiren
Registration numbers
CAS Number
Properties
Physical Property
Solubility
Water
Methanol
Melting Point
96-101°C
Apperance
White Solid
Safety Information
Storage Condition
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
An orally active, synthetic nonpeptide renin inhibitor. Antihypertensive.
Molecular Spectra
No Data Available
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References
• Lefevre, G., et al.: J. Immunoassay, 21, 65 (2000)
• Allikments, K., et al.: Curr. Opin. Invest. Drugs, 3, 1479 (2000)
• Wood, J.M., et al.: Biochem. Biophys. Res. Commun., 308, 698 (2000)
• Grandman, A.H., et al.: Circulation, 111, 1012 (2000)