Substance
ID:373111
Names and Identifiers
Synonyms
ValdoxanAgomelatineS 20098N-[2-(7-Methoxy-1-naphthyl)ethyl]acetamideN-[2-(7-Methoxy-1-naphthalenyl)ethyl]acetamide
IUPAC name
N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
IUPAC Traditional name
agomelatine
Registration numbers
CAS Number
Properties
Physical Property
Melting Point
107-109°C
Solubility
Methanol
Chloroform
Apperance
White Solid
Safety Information
Storage Condition
-20°C Freezer
MSDS Link
Product Information
Certificate of Analysis
Molecule Details
Agomelatine is a melatoninergic agonist and selective antagonist of 5-HT2C receptors, and has been shown to be active in several animal models of depression. Agomelatine (S20098) displayed pKi values of 6.4 and 6.2 at native (porcine) and cloned, human
Molecular Spectra
No Data Available
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References
• Yous, S., et al.: J. Med. Chem., 35, 1484 (1992)
• Cajochen, C., et al.: J. Pineal Res., 35, 149 (1992)
• Zhdanova, I., et al.: J. Clin. Endocrinol. Metab., 86, 4727 (1992)