Substance
ID:373072
S-(5'-Adenosyl)-L-methionine Disulfate Salt (Synthetic)(Mixture of Diastereomers)
Names and Identifiers
IUPAC name
[(3S)-3-amino-3-carboxypropyl]({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl})methylsulfanium chloride
IUPAC Traditional name
SAMe chloride
Synonyms
5'-[[(3S)-3-Amino-3-carboxypropyl]methylsulfonio]-5'-deoxyadenosine DisulfateL-S-Adenosylmethionin DisulfateS-(5'-Adenosyl)-L-methionine Disulfate Salt (Synthetic)(Mixture of Diastereomers)5'-[(L-3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine DisulfateAdemetionine DisulfateS-Adenosylmethionine DisulfateActive Methionine DisulfateS-Adenosyl-L-methionine Disulfate
Registration numbers
No Data Available
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Properties
Physical Property
Melting Point
121-125°C
Solubility
Methanol
Water
Apperance
Light Beige to Pale Brown Solid
Product Information
Certificate of Analysis
Safety Information
MSDS Link
Storage Condition
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Molecule Details
Methyl donor; cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also
Molecular Spectra
No Data Available
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References
• Friedel, H., et al.: Drugs, 38, 389 (1989)
• Lu, S., et al.: Int. J. Biochem. Cell Biol., 32, 391 (1989)
• Amin, K., et al.: Pharm. Res., 18, 914 (1989)