Substance
ID:371938
Names and Identifiers
IUPAC Traditional name
β-mercaptoethanol
IUPAC name
2-sulfanylethan-1-ol
Synonyms
2-羟基乙硫醇β-巯基乙醇BME硫代乙二醇2-Mercaptoethanol2-巯基乙醇2-HydroxyethylmercaptanThioethylene glycolβ-Mercaptoethanol
Properties
Pharmacology Properties
Target Organ
Heart, Liver
Physical Property
Flash Point
68 °C
154.4 °F
Vapor Pressure
1 mmHg ( 20 °C)
Refractive Index
n20/D 1.500(lit.)
Vapor Density
2.69 (vs air)
Boiling Point
157 °C(lit.)
Density
1.114 g/mL at 25 °C(lit.)
Product Information
Purity
≥99.0%
Linear Formula
HSCH2CH2OH
Grade
SAJ special grade
Concentration
14.3 M (pure liquid)
Safety Information
Explode Limits
18 %
GHS Pictograms
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Hazardous to the aquatic environment
Acute hazard, category1
Chronic hazard, categories 1,2
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
RID/ADR
UN 2966 6.1/PG 2
UN Number
2966
GHS Precautionary statements
P261-P273-P280-P301+P310-P302+P350-P305+P351+P338
European Hazard Symbols
Nature polluting (N)
Toxic (T)Hazard Class
6.1
GHS Hazard statements
H301+H331-H310-H315-H317-H318-H373-H410
Risk Statements
23/24/25-38-41-43-48/22-50/53
Personal Protective Equipment
Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Packing Group
2
GHS Signal Word
Danger
Safety Statements
26-36/37/39-45-60-61
German water hazard class
3
RTECS
KL5600000
Molecule Details
Application
BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.
BME is suitable for reducing protein disulfide bonds prior to polyacrylamide gel electrophoresis and is usually included in a sample buffer for SDS-PAGE at a concentration of 5%. Cleaving intermolecular (between subunits) disulfide bonds allows the subunits of a protein to separate independently on SDS-PAGE. Cleaving intramolecular (within subunit) disulfide bonds allows the subunits to become completely denatured so that each peptide migrates according to its chain length with no influence due to secondary structure.
Molecular Spectra
No Data Available
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References
No Data Available
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