Substance
ID:371356
Names and Identifiers
Synonyms
咖啡因1,3,7-三甲基黄嘌呤Caffeine1,3,7-Trimethylxanthine
IUPAC Traditional name
caffeine
IUPAC name
1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione
Properties
Safety Information
European Hazard Symbols
Harmful (Xn)Risk Statements
22
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
UN Number
1544
RTECS
EV6475000
GHS Signal Word
Warning
GHS Hazard statements
H302
Packing Group
3
German water hazard class
1
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
RID/ADR
UN 1544 6.1/PG 3
Hazard Class
6.1
Physical Property
Melting Point
234-236.5 °C(lit.)
Pharmacology Properties
Gene Information
human ... ADORA1(134), PDE4B(5142)
Product Information
Purity
≥98.5%
Empirical Formula (Hill Notation)
C8H10N4O2
Grade
SAJ special grade
Molecule Details
Biochem/physiol Actions
A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.
A central nervous system stimulant believed to act through adenosine receptors and monoamine neurotransmitters. It is an adenosine receptor antagonist and adenosine 3′,5′-cyclic monophosphate (cAMP) phosphodiesterase inhibitor. Thus, levels of cAMP increase in cells following treatment with caffeine. It has been reported to affect cellular calcium levels, releasing calcium from intracellular stores. It overrides the cell cycle effects of various chemicals such as protease inhibitors, preventing apoptosis; and it has been shown to inhibit cellular DNA repair mechanisms.
Molecular Spectra
No Data Available
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References
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