Substance

ID:366372

Names and Identifiers
IUPAC Traditional name
N-ethylmaleimide
IUPAC name
1-ethyl-2,5-dihydro-1H-pyrrole-2,5-dione
Synonyms
NEMN-EthylmaleimideN-乙基马来酰亚胺
Registration numbers
MDL Number
CAS Number
EC Number
Beilstein Number
PubChem SID
Properties
Product Information
Antion Traces
chloride (Cl-): ≤50 mg/kg
sulfate (SO42-): ≤100 mg/kg
Purity
≥99.0% (HPLC)
Cation Traces
Ni: ≤50 mg/kg
Na: ≤100 mg/kg
Zn: ≤50 mg/kg
Co: ≤50 mg/kg
K: ≤100 mg/kg
Pb: ≤50 mg/kg
Ca: ≤50 mg/kg
Fe: ≤50 mg/kg
Cd: ≤50 mg/kg
Cu: ≤50 mg/kg
Grade
purum p.a.
Empirical Formula (Hill Notation)
C6H7NO2
Ignition Residue
≤0.05%
Safety Information
MSDS Link
GHS Precautionary statements
P264-P280-P301+P310-P305+P351+P338-P310
GHS Pictograms
GHS05
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
GHS06
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
RID/ADR
UN 2928 6.1/PG 2
GHS Signal Word
Danger
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
26-28-36/37/39-45
Storage Temperature
2-8°C
GHS Hazard statements
H300-H311-H314-H317
European Hazard Symbols
Highly toxic Highly toxic (T+)
Risk Statements
21-28-34-43
RTECS
UX9625000
German water hazard class
3
Pharmacology Properties
Gene Information
human ... SLC6A3(6531), SLC6A4(6532)
Physical Property
Boiling Point
210 °C(lit.)
Flash Point
163.4 °F
73 °C
Melting Point
43-46 °C
43-46 °C(lit.)
Molecule Details
Application
Reagent for the covalent modification of cysteine residues in proteins.
Biochem/physiol Actions
Augments currents from native M-channels in sympathetic neurons and acts as an opener for KCNQ2, KCNQ4 and KCNQ5 channels.
Sulfhydryl alkylating agent that inactivates NADP-dependent isocitrate dehydrogenase and many endonucleases.
Molecular Spectra
No Data Available
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References
No Data Available
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