Substance
ID:365913
Names and Identifiers
IUPAC Traditional name
zidovudine
IUPAC name
1-[(2R,4S,5S)-4-azido-5-(hydroxymethyl)oxolan-2-yl]-5-methyl-1,2,3,4-tetrahydropyrimidine-2,4-dione
Synonyms
azidothymidine3′-Azido-3′-deoxythymidine齐多夫定3′-叠氮-3′-脱氧胸苷ZDVZidovudineAZT叠氮胸苷
Properties
Physical Property
Melting Point
113-115 °C(lit.)
Solubility
H2O: soluble50 mg/mL, clear, colorless to slightly yellow
Safety Information
Risk Statements
40
European Hazard Symbols
Harmful (Xn)GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Hazard statements
H351
GHS Signal Word
Warning
MSDS Link
GHS Precautionary statements
P281
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
36/37/39-45
German water hazard class
3
Storage Temperature
-20°C
RTECS
XP2072000
Product Information
Empirical Formula (Hill Notation)
C10H13N5O4
Impurities
≤0.5% water
Purity
≥99.0% (HPLC)
Molecule Details
Biochem/physiol Actions
Reverse transcriptase inhibitor active against HIV-1 virus.
Other Notes
A potent, selective inhibitor of human immunodeficiency virus replication in MT-4 and ATH8 cells1
Reverse transcriptase inhibitor active against HIV-1 virus.
Other Notes
A potent, selective inhibitor of human immunodeficiency virus replication in MT-4 and ATH8 cells1
Molecular Spectra
No Data Available
Click here to submit data
References
No Data Available
Click here to submit data