Substance

ID:365259

(R)-5-(Hydroxymethyl)-2-pyrrolidinone

Names and Identifiers
IUPAC name
(5R)-5-(hydroxymethyl)pyrrolidin-2-one
IUPAC Traditional name
(5R)-5-(hydroxymethyl)pyrrolidin-2-one
Synonyms
D-焦谷氨醇(R)-(-)-5-(羟甲基)-2-吡咯烷酮D-Pyroglutaminol(R)-5-(Hydroxymethyl)-2-pyrrolidinone
Registration numbers
CAS Number
PubChem SID
Beilstein Number
MDL Number
Properties
Product Information
Grade
puriss.
Empirical Formula (Hill Notation)
C5H9NO2
Purity
≥99.0% (sum of enantiomers, HPLC)
Physical Property
Melting Point
79-85 °C
Optical Rotation
[α]/D -30.5±2.0°, c = 5 in ethanol
Safety Information
GHS Signal Word
Warning
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Risk Statements
36/37/38
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P261-P305+P351+P338
Safety Statements
26-36
GHS Hazard statements
H315-H319-H335
European Hazard Symbols
Irritant Irritant (Xi)
German water hazard class
3
MSDS Link
Molecule Details
Other Notes
Versatile chiral building block and auxiliary, used e.g. for the synthesis of azaprostaglandins or 4,5-diaminovalerate1,2,3; The bicyclic N,O-benzylidene acetal allows enantioselective derivatization of the pyrrolidinone nucleus4,5
Molecular Spectra
No Data Available
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References
No Data Available
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