Substance
ID:364870
Names and Identifiers
IUPAC Traditional name
bis(quinine) sulfuric acid dihydrate
Synonyms
Quinine sulfate (2:1) (salt) dihydrateQuinine hemisulfate salt monohydrate奎宁 半硫酸盐 一水合物Chinini sulfas硫酸奎宁
IUPAC name
bis((R)-[(2S,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol) sulfuric acid dihydrate
Registration numbers
Beilstein Number
CAS Number
MDL Number
PubChem SID
Properties
Product Information
Pharmacopeia
testing & handling conforms to Pharmacopeia
Empirical Formula (Hill Notation)
C20H24N2O2 · 0.5H2O4S · H2O
Grade
Ph Eur
Safety Information
Risk Statements
36/37/38
GHS Signal Word
Warning
German water hazard class
3
GHS Hazard statements
H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
GHS Precautionary statements
P261-P305+P351+P338
Safety Statements
26
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
European Hazard Symbols
Irritant (Xi)MSDS Link
Physical Property
Melting Point
~225 °C (dec.)(lit.)
Molecule Details
Application
Used to study the toxicity of heme (FP)-complexes.
Biochem/physiol Actions
Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
Used to study the toxicity of heme (FP)-complexes.
Biochem/physiol Actions
Potassium channel blocker. Antimalarial, anticholinergic, antihypertensive, and hypoglycemic agent; alkaloid originally isolated from the Cinchona family of South American trees. Inhibits mitochondrial ATP-regulated potassium channel. Used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
Molecular Spectra
No Data Available
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References
No Data Available
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