Substance
ID:364667
Names and Identifiers
IUPAC Traditional name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1H-purin-6-one
Synonyms
Hypoxanthine 9-β-D-ribofuranosideInosine(-)-Inosine
IUPAC name
9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6,9-dihydro-1H-purin-6-one
Properties
Physical Property
Optical Rotation
[α]20/D -76±2°, c = 1% in 0.1 M NaOH
Melting Point
222-226 °C (dec.)(lit.)
Safety Information
MSDS Link
German water hazard class
2
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Product Information
Purity
≥99.0% (HPLC)
Empirical Formula (Hill Notation)
C10H12N4O5
Quality
crystallized
Ignition Residue
≤0.05%
Molecule Details
Biochem/physiol Actions
Inosine is a potent stimulator of nerve growth factor (NGF) induced neurite outgrowth. The elevated levels of inosine in brain following injury are associated with the increased expression proteins related to axonal regeneration and growth. Mice given inosine demonstrated enhanced recovery of fine motor control following ischemic brain damage. Inosine may be used in studies of the process A-to-I RNA editing.
Inosine is a potent stimulator of nerve growth factor (NGF) induced neurite outgrowth. The elevated levels of inosine in brain following injury are associated with the increased expression proteins related to axonal regeneration and growth. Mice given inosine demonstrated enhanced recovery of fine motor control following ischemic brain damage. Inosine may be used in studies of the process A-to-I RNA editing.
Molecular Spectra
No Data Available
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References
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