Substance
ID:363466
Names and Identifiers
IUPAC name
(3aS,8aR)-1,3a,8-trimethyl-1H,2H,3H,3aH,8H,8aH-pyrrolo[2,3-b]indol-5-yl N-methylcarbamate
Synonyms
Physostigmine伊色林毒扁豆碱Eserine
IUPAC Traditional name
physostigmine
Registration numbers
CAS Number
Beilstein Number
EC Number
MDL Number
PubChem SID
Properties
Physical Property
Flash Point
>100 °C
>212 °F
Optical Rotation
[α]20/D -77±1°, c = 1.7% in chloroform
Melting Point
102-106 °C
102-104 °C(lit.)
Pharmacology Properties
Gene Information
human ... ACHE(43), APP(351), BCHE(590)mouse ... Ache(11423), Bche(12038), Chrm1(12669)rat ... Ache(83817), Bche(65036), Chrm2(81645)
Safety Information
GHS Signal Word
Danger
European Hazard Symbols
Highly toxic (T+)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
GHS Hazard statements
H300-H330
UN Number
1544
Packing Group
1
Storage Temperature
2-8°C
Hazard Class
6.1
MSDS Link
GHS Precautionary statements
P260-P264-P284-P310
RTECS
TJ2100000
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Risk Statements
26/28
German water hazard class
3
RID/ADR
UN 1544 6.1/PG 1
Safety Statements
25-45
Product Information
Empirical Formula (Hill Notation)
C15H21N3O2
Purity
≥98.0% (N)
Molecule Details
Biochem/physiol Actions
Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.
Acetylcholinesterase inhibitor that crosses the blood-brain barrier and forms a carbamylated enzyme complex with acetyl cholinesterase that degrades slowly.
Molecular Spectra
No Data Available
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References
No Data Available
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