Substance
ID:363001
Names and Identifiers
IUPAC Traditional name
sodium levothyroxine(1-) pentahydrate
IUPAC name
sodium (2S)-2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoate pentahydrate
Synonyms
T4Sodium levothyroxine3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt3-[4-(4-羟基-3,5-二碘苯氧基)-3,5-二碘苯基]-L-丙氨酸 钠盐左旋甲状腺素钠L-Thyroxine sodium salt pentahydrateL-甲状腺素 钠盐 五水合物
Registration numbers
EC Number
CAS Number
Beilstein Number
MDL Number
Properties
Safety Information
German water hazard class
3
MSDS Link
Personal Protective Equipment
Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage Temperature
2-8°C
RTECS
YP2833760
Product Information
Impurities
~10% water
Linear Formula
HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O
Purity
≥97.0% (sum of enantiomers, HPLC)
Physical Property
Melting Point
207-210 (dec.)(lit.)
Optical Rotation
[α]20/D +16±1°, c = 2% in ethanol/1 M HCl (4:1)
Molecule Details
Application
Literatur s. 89405, L-Thyroxine
Biochem/physiol Actions
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.
Literatur s. 89405, L-Thyroxine
Biochem/physiol Actions
L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.
Molecular Spectra
No Data Available
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References
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