Substance
ID:362834
Names and Identifiers
IUPAC Traditional name
dexamethasone
Synonyms
德沙美松地塞米松9α-氟-16α-甲基氢化泼尼松Dexamethasone21α-乙酰氧基-9α-氟-11β,17α-二羟基-16α-甲基孕甾-1,4-二烯-3,20-二酮9-氟-11,17,21-三羟基-16-甲基(11b,16a)-孕甾-1,4-二烯-3,20-二酮9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dionePrednisolone F(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione9α-Fluoro-16α-methylprednisoloneDexamethasonum地塞米松
IUPAC name
(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Registration numbers
EC Number
Beilstein Number
MDL Number
CAS Number
PubChem SID
Properties
Safety Information
GHS Hazard statements
H315-H317-H319-H334-H335
GHS Precautionary statements
P261-P280-P305+P351+P338-P342+P311
Safety Statements
22-26-36/37-45
German water hazard class
2
RTECS
TU3980000
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
European Hazard Symbols
Harmful (Xn)MSDS Link
GHS Signal Word
Danger
Risk Statements
36/37/38-42/43
Product Information
Grade
Ph Eur
Empirical Formula (Hill Notation)
C22H29FO5
Pharmacopeia
testing & handling conforms to Pharmacopeia
Pharmacology Properties
Gene Information
human ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908)mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Ptgs2(19225), Tnf(21926)rat ... Ar(24208), Nr3c1(24413), Tnf(24835)
Physical Property
Melting Point
262-264 °C(lit.)
Molecule Details
Biochem/physiol Actions
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
Molecular Spectra
No Data Available
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References
No Data Available
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