Substance
ID:362790
Names and Identifiers
IUPAC Traditional name
chamomile
IUPAC name
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Synonyms
4′,5,7-TrihydroxyflavoneApigenin
Registration numbers
EC Number
MDL Number
CAS Number
Beilstein Number
Properties
Product Information
Impurities
≤2% water
Purity
≥75% (HPLC)
Biological Source
from parsley
Empirical Formula (Hill Notation)
C15H10O5
Safety Information
GHS Signal Word
Warning
GHS Precautionary statements
P261-P305+P351+P338
GHS Hazard statements
H315-H319-H335
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
RTECS
LK9276000
Safety Statements
26-36
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Storage Temperature
-20°C
MSDS Link
Risk Statements
36/37/38
European Hazard Symbols
Irritant (Xi)German water hazard class
3
Physical Property
Melting Point
>300 °C(lit.)
Molecule Details
Biochem/physiol Actions
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53.Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C1 and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53.Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C1 and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.
Molecular Spectra
No Data Available
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References
No Data Available
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