Substance
ID:362535
Names and Identifiers
IUPAC Traditional name
dexamethasone
Synonyms
德沙美松地塞米松9α-氟-16α-甲基氢化泼尼松Dexamethasone21α-乙酰氧基-9α-氟-11β,17α-二羟基-16α-甲基孕甾-1,4-二烯-3,20-二酮9-氟-11,17,21-三羟基-16-甲基(11b,16a)-孕甾-1,4-二烯-3,20-二酮9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dionePrednisolone F(11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione9α-Fluoro-16α-methylprednisolone
IUPAC name
(1R,2S,10S,11S,13R,14R,15S,17S)-1-fluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.02,7.011,15]heptadeca-3,6-dien-5-one
Registration numbers
EC Number
Beilstein Number
MDL Number
CAS Number
PubChem SID
Properties
Safety Information
European Hazard Symbols
Harmful (Xn)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
RTECS
TU3980000
GHS Signal Word
Danger
MSDS Link
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
German water hazard class
2
Safety Statements
22-26-36/37-45
GHS Hazard statements
H315-H317-H319-H334-H335
GHS Precautionary statements
P261-P280-P305+P351+P338-P342+P311
Storage Temperature
2-8°C
Risk Statements
36/37/38-42/43
Product Information
Empirical Formula (Hill Notation)
C22H29FO5
Grade
VETRANAL™, analytical standard
Physical Property
Melting Point
262-264 °C(lit.)
Pharmacology Properties
Gene Information
human ... ABCB1(5243), CYP3A4(1576), IL4(3565), IL5(3567), NR3C1(2908)mouse ... Abcb1a(18671), Abcb1b(18669), Ifng(15978), Nos2(18126), Ptgs2(19225), Tnf(21926)rat ... Ar(24208), Nr3c1(24413), Tnf(24835)
Molecule Details
Biochem/physiol Actions
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase.
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
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References
No Data Available
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