Substance
ID:362412
Names and Identifiers
IUPAC name
bis((4S,5S,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide) ethanol hydrate dihydrochloride
IUPAC Traditional name
bis((4S,5S,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-4a,5,5a,6-tetrahydro-4H-tetracene-2-carboxamide) ethyl alcohol hydrate dihydrochloride
Synonyms
多西环素盐酸盐半乙醇化物半水合物Doxycycline hyclate多西环素 单盐酸半乙醇半水合物Doxycycline hydrochloride hemiethanolate hemihydrate
Properties
Safety Information
GHS Signal Word
Warning
German water hazard class
3
GHS Precautionary statements
P261-P305+P351+P338
Safety Statements
26
Risk Statements
22-36/37/38
GHS Hazard statements
H302-H315-H319-H335
MSDS Link
European Hazard Symbols
Harmful (Xn)GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Product Information
Empirical Formula (Hill Notation)
C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O
Impurities
≤7% ethanol
≤5% water
Purity
≥98.0% (TLC)
Physical Property
Solubility
H2O: soluble50 mg/mL, clear, yellow-green
Molecule Details
Application
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Biochem/physiol Actions
Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi1. It is a broad spectrum inhibitor of matrix metalloproteinases in vivo.
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Biochem/physiol Actions
Doxycycline hyclate inhibits the inflammatory response to the Lyme Disease Spirochete Borrelia burgdorferi1. It is a broad spectrum inhibitor of matrix metalloproteinases in vivo.
Molecular Spectra
No Data Available
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References
No Data Available
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