Substance

ID:362271

Names and Identifiers
IUPAC Traditional name
progesterone
IUPAC name
(1S,2R,10S,11S,14S,15S)-14-acetyl-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Synonyms
4-pregnene-3,20-dioneProgesterone孕酮孕烯二酮
Registration numbers
EC Number
Beilstein Number
MDL Number
CAS Number
PubChem SID
Properties
Safety Information
GHS Signal Word
Warning
European Hazard Symbols
Harmful Harmful (Xn)
MSDS Link
GHS Hazard statements
H351
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Risk Statements
40
German water hazard class
3
GHS Precautionary statements
P281
RTECS
TW0175000
Safety Statements
36/37
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Product Information
Grade
VETRANAL™, analytical standard
Empirical Formula (Hill Notation)
C21H30O2
Pharmacology Properties
Gene Information
human ... ABCB1(5243), AR(367), CYP2C9(1559), EBP(10682), ESR1(2099), ESR2(2100), NR3C1(2908), NR3C2(4306), PGR(5241), SERPINA6(866)mouse ... Esr1(13982)rat ... Ar(24208), Nr3c1(24413), Pgr(25154)
Physical Property
Melting Point
128-132 °C(lit.)
Molecule Details
Other Notes
Steroid hormone produced by the corpus luteum.
Biochem/physiol Actions
Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
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References
No Data Available
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