Substance
ID:361497
Names and Identifiers
IUPAC Traditional name
chamomile
IUPAC name
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
Synonyms
4′,5,7-TrihydroxyflavoneApigenin
Registration numbers
EC Number
MDL Number
CAS Number
Beilstein Number
Properties
Product Information
Grade
analytical standard
Empirical Formula (Hill Notation)
C15H10O5
Shelf Life
(limited shelf life, expiry date on the label)
Purity
≥99% (HPLC)
Physical Property
Melting Point
>300 °C(lit.)
Safety Information
GHS Hazard statements
H315-H319-H335
RTECS
LK9276000
German water hazard class
3
Safety Statements
26-36
GHS Signal Word
Warning
European Hazard Symbols
Irritant (Xi)MSDS Link
Risk Statements
36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P261-P305+P351+P338
Storage Temperature
2-8°C
Molecule Details
Biochem/physiol Actions
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53.Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C1 and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.
A plant flavonoid that has been found to inhibit cell proliferation by arresting the cell cycle at the G2/M phase. Inhibition of growth through cell cycle arrest and induction of apoptosis appear to be related to induction of p53.Inhibits PMA-mediated tumor promotion by inhibiting protein kinase C1 and the resulting suppression of oncogene expression. It has also been reported to inhibit topoisomerase I-catalyzed DNA re-ligation and enhance gap junctional intercellular communication.
Molecular Spectra
No Data Available
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References
No Data Available
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