Substance

ID:361336

MolImageID:73266

Tetracycline hydrochloride

Sigma Aldrich
Names and Identifiers
IUPAC name
(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride
IUPAC Traditional name
tetracycline hydrochloride
Synonyms
四环素 盐酸盐Tetracycline hydrochloride
Registration numbers
EC Number
200-593-8
CAS Number
64-75-5
MDL Number
MFCD00078142
Beilstein Number
3844873
Properties
Physical Property
Melting Point
220-223 °C(lit.)
Product Information
Empirical Formula (Hill Notation)
C22H24N2O8 · HCl
Pharmacopeia Traceability
traceable to PhEur T060000
traceable to BP 480
traceable to USP 1651009
Safety Information
German water hazard class
2
GHS Signal Word
Warning
GHS Hazard statements
H315-H319-H335-H361-H362
European Hazard Symbols
Harmful Harmful (Xn)
MSDS Link
Download link
Risk Statements
63-36/37/38-64
RTECS
QI9100000
Storage Temperature
2-8°C
GHS Precautionary statements
P261-P263-P281-P305+P351+P338
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Safety Statements
26-36
Molecule Details
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.Mode of Resistance: Loss of cell wall permeability.
Molecular Spectra
No Data Available
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References
No Data Available
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