Substance
ID:360582
Names and Identifiers
IUPAC name
(2S,5R,6R)-6-(2-carboxy-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
IUPAC Traditional name
carbenicillin
Synonyms
α-Carboxybenzylpenicillin 溶液α-Carboxybenzylpenicillin solution克雷伯氏菌选择性添加剂羧苄青霉素Klebsiella Selective SupplementCarbenicillin
Properties
Safety Information
GHS Signal Word
Danger
GHS Precautionary statements
P261-P280-P342+P311
RTECS
ON9104700
European Hazard Symbols
Harmful (Xn)Safety Statements
22-36/37-45
MSDS Link
Storage Temperature
2-8°C
GHS Hazard statements
H317-H334
German water hazard class
3
Risk Statements
42/43
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Product Information
Shelf Life
(limited shelf life, expiry date on the label)
Empirical Formula (Hill Notation)
C17H18N2O6S
Grade
for microbiology
Molecule Details
Components
(per vial, sufficient for 500 ml medium)Carbenicillin 25 mg
Application
For selective isolation and detection of Klebsiella species.
Biochem/physiol Actions
The antibiotic carbenicillin, an ampicillin analog, is a commonly used selection agent that binds and inhibits enzymes involved in the synthesis of the bacterial cell wall. It is active against most isolates of Pseudomonas aerogenosa and certain indole-positive Proteus strains that are resistant to ampicillin. The gene conferring resistance to ampicillin and its analogs, ampr, codes for the enzyme β-lactamase. Carbenicillin is less sensitive to β-lactamase than ampicillin. In addition it has a superior stability at low pH. Experiments have shown that the use of carbenicillin in place of ampicillin helps prevent overgrowth of satellite colonies. Effective concentration: 50 to 100 μg/ml.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 15821.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
(per vial, sufficient for 500 ml medium)Carbenicillin 25 mg
Application
For selective isolation and detection of Klebsiella species.
Biochem/physiol Actions
The antibiotic carbenicillin, an ampicillin analog, is a commonly used selection agent that binds and inhibits enzymes involved in the synthesis of the bacterial cell wall. It is active against most isolates of Pseudomonas aerogenosa and certain indole-positive Proteus strains that are resistant to ampicillin. The gene conferring resistance to ampicillin and its analogs, ampr, codes for the enzyme β-lactamase. Carbenicillin is less sensitive to β-lactamase than ampicillin. In addition it has a superior stability at low pH. Experiments have shown that the use of carbenicillin in place of ampicillin helps prevent overgrowth of satellite colonies. Effective concentration: 50 to 100 μg/ml.
Other Notes
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 15821.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Molecular Spectra
No Data Available
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References
No Data Available
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