Substance

ID:360457

Ampicillin trihydrate

Names and Identifiers
IUPAC name
(2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate
IUPAC Traditional name
ampicillin trihydrate
Synonyms
氨苄青霉素Ampicillin trihydrate氨苄西林 三水合物D-(-)-α-Aminobenzylpenicillin
Registration numbers
MDL Number
Beilstein Number
EC Number
CAS Number
PubChem SID
Properties
Safety Information
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Risk Statements
36/37/38-42/43
GHS Pictograms
GHS07
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Signal Word
Danger
RTECS
XH8425000
Safety Statements
22-26-36/37
Storage Temperature
2-8°C
GHS Hazard statements
H315-H317-H319-H334-H335
European Hazard Symbols
Harmful Harmful (Xn)
German water hazard class
2
MSDS Link
GHS Precautionary statements
P261-P280-P305+P351+P338-P342+P311
Physical Property
Melting Point
198-200 °C (dec.)(lit.)
Product Information
Empirical Formula (Hill Notation)
C16H19N3O4S · 3H2O
Grade
VETRANAL™, analytical standard
Molecule Details
Application
Commission Regulation (EU) No 37/2010 of 22 December 2009 on pharmacologically active substances and their classification regarding maximum residue limits in foodstuffs of animal origin
Biochem/physiol Actions
A β-lactam antibiotic with an amino group side chain attached to the penicillin structure. Penicillin derivative that inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli . Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Legal Information
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Molecular Spectra
No Data Available
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References
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