Substance

ID:360317

Names and Identifiers
IUPAC Traditional name
hydrocortisone
Synonyms
17-HydroxycorticosteroneCortisol11β,17α,21-Trihydroxypregn-4-ene-3,20-dioneReichstein’s substance M氢化皮质酮Kendall’s compound F氢化可的松4-Pregnene-11β,17α,21-triol-3,20-dione氢化泼尼松龙皮质醇Hydrocortisone11β,17α,21-三羟基孕甾-4-烯-3,20-二酮17-羟基皮质甾酮4-孕烯-11β,17α,21-三醇-3,20-二酮
IUPAC name
(1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.02,7.011,15]heptadec-6-en-5-one
Registration numbers
EC Number
200-020-1
CAS Number
50-23-7
MDL Number
MFCD00011654
Beilstein Number
1354819
Properties
Product Information
Empirical Formula (Hill Notation)
C21H30O5
Grade
VETRANAL™, analytical standard
Safety Information
Risk Statements
63
RTECS
GM8925000
Safety Statements
36/37
GHS Hazard statements
H361
GHS Precautionary statements
P281
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Signal Word
Warning
German water hazard class
3
MSDS Link
Download link
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
European Hazard Symbols
Harmful Harmful (Xn)
Physical Property
Melting Point
211-214 °C(lit.)
Molecule Details
Biochem/physiol Actions
Primary glucocorticoid secreted by the adrenal cortex. It has three times the anti-inflammatory potency of corticosterone but much lower Na2+ retention potency.
Legal Information
VETRANAL is a trademark of Sigma-Aldrich Co. LLC
Molecular Spectra
No Data Available
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References
No Data Available
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