Substance
ID:359942
Names and Identifiers
Synonyms
氨苄西林氨苄青霉素AmpicillinD-(-)-α-Aminobenzylpenicillin
IUPAC name
(2S,5R,6R)-6-[(2R)-2-amino-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
IUPAC Traditional name
ampicillin
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
Properties
Product Information
Purity
≥98.0% (NT)
Impurities
≤1% water
Empirical Formula (Hill Notation)
C16H19N3O4S
Safety Information
MSDS Link
GHS Precautionary statements
P261-P280-P305+P351+P338-P342+P311
Risk Statements
36/37/38-42/43
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Faceshields, Gloves
RTECS
XH8350000
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
Safety Statements
22-26-36/37
European Hazard Symbols
Harmful (Xn)GHS Signal Word
Danger
GHS Hazard statements
H315-H317-H319-H334-H335
German water hazard class
2
Storage Temperature
2-8°C
Physical Property
Melting Point
208 °C (dec.)(lit.)
Optical Rotation
[α]20/D +295±5°, c = 0.2% in H2O
Solubility
1 M NH4OH: soluble50 mg/mL, clear, colorless
Molecule Details
Biochem/physiol Actions
A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Inhibits cell wall synthesis in Escherichia coli1; In the purification of penicillin acylase2; Enhances luminol chemiluminescence.3
A β-lactam antibiotic with an amino group attached to the penicillin structure. Inhibits bacterial cell-wall synthesis (peptidoglycan cross-linking) by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Bactericidal only to growing Escherichia coli. Mode of resistance: Cleavage of β-lactam ring of ampicillin by β-lactamase. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Inhibits cell wall synthesis in Escherichia coli1; In the purification of penicillin acylase2; Enhances luminol chemiluminescence.3
Molecular Spectra
No Data Available
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References
No Data Available
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