Substance
ID:359849
Names and Identifiers
IUPAC Traditional name
colchicine
Synonyms
秋水仙素Colchicine
IUPAC name
N-[(10S)-3,4,5,14-tetramethoxy-13-oxotricyclo[9.5.0.02,7]hexadeca-1(16),2,4,6,11,14-hexaen-10-yl]acetamide
Registration numbers
CAS Number
Beilstein Number
EC Number
MDL Number
Properties
Product Information
Impurities
≤3% water
≤10% ethyl acetate + H2O
Empirical Formula (Hill Notation)
C22H25NO6
Purity
≥96.0% (HPLC)
Safety Information
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Corrosive to metals, category 1
Skin corrosion, categories 1A,1B,1C
Serious eye damage, category 1
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
Risk Statements
46-28
GHS Precautionary statements
P201-P260-P264-P280-P284-P301+P310
UN Number
1544
German water hazard class
3
RTECS
GH0700000
GHS Hazard statements
H300+H330-H318-H340
MSDS Link
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
Safety Statements
53-45
European Hazard Symbols
Highly toxic (T+)RID/ADR
UN 1544 6.1/PG 1
GHS Signal Word
Danger
Hazard Class
6.1
Packing Group
1
Physical Property
Melting Point
150-160 °C (dec.)(lit.)
Molecule Details
Other Notes
Binds specifically with tubulin thus interfering with microtubule organization.1
Binds specifically with tubulin thus interfering with microtubule organization.1
Molecular Spectra
No Data Available
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References
No Data Available
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