Substance
ID:358773
Names and Identifiers
IUPAC name
3-methyl-3-nitroso-1-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea
IUPAC Traditional name
streptozocin
Synonyms
StreptozocinN-(Methylnitrosocarbamoyl)-α-D-glucosamineStreptozotocin
Registration numbers
CAS Number
Beilstein Number
EC Number
MDL Number
Properties
Product Information
Empirical Formula (Hill Notation)
C8H15N3O7
Purity
≥98.0% (HPLC)
Safety Information
Personal Protective Equipment
Eyeshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements
P201-P308+P313
RTECS
LZ5775000
Storage Temperature
-20°C
European Hazard Symbols
Toxic (T)GHS Hazard statements
H350
Safety Statements
53-45
German water hazard class
3
GHS Pictograms
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
MSDS Link
GHS Signal Word
Danger
Risk Statements
45
Physical Property
Melting Point
121 °C (dec.)(lit.)
Molecule Details
Biochem/physiol Actions
An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets; induces death of insulin-secreting cells, producing an animal model of diabetes. Potent DNA methylating agent that induces chromosomal breakage.1 Cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.
An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets; induces death of insulin-secreting cells, producing an animal model of diabetes. Potent DNA methylating agent that induces chromosomal breakage.1 Cytotoxic to neuroendocrine tumor cell lines that express the GLUT2 glucose transporter.
Molecular Spectra
No Data Available
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References
No Data Available
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