Substance
ID:358033
Names and Identifiers
Synonyms
胆钙化醇活化7-脱氢胆固醇Cholecalciferol活化7-脱氢胆甾醇胆骨化醇(+)-维生素 D37-Dehydrocholesterol activatedCalciolActivated 7-dehydrocholesterol(+)-Vitamin D3
IUPAC name
(1S)-3-{2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
IUPAC Traditional name
cholecalciferol
Registration numbers
Beilstein Number
CAS Number
MDL Number
EC Number
Properties
Physical Property
Melting Point
83-86 °C(lit.)
83-86 °C
Optical Rotation
[α]20/D +109±3°, c = 2% in ethanol
Safety Information
RID/ADR
UN 2811 6.1/PG 2
German water hazard class
2
GHS Hazard statements
H301-H311-H330-H372
MSDS Link
RTECS
VS2900000
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Precautionary statements
P260-P280-P284-P301+P310-P310
European Hazard Symbols
Highly toxic (T+)UN Number
2811
Packing Group
2
Risk Statements
24/25-26-48/25
Storage Temperature
2-8°C
Hazard Class
6.1
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
GHS Signal Word
Danger
Safety Statements
28-36/37-45
Product Information
Empirical Formula (Hill Notation)
C27H44O
Purity
≥99.0% (sum of enantiomers, HPLC)
Molecule Details
Other Notes
Review: Vitamin D: Recent advances1
Unit Definition
1 U corresponds to 1 international U according to commentary-DAB, 8th issue, 38 (1981)
Biochem/physiol Actions
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
Review: Vitamin D: Recent advances1
Unit Definition
1 U corresponds to 1 international U according to commentary-DAB, 8th issue, 38 (1981)
Biochem/physiol Actions
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
Molecular Spectra
No Data Available
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References
No Data Available
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