Substance
ID:358033
Names and Identifiers
Synonyms
胆钙化醇活化7-脱氢胆固醇Cholecalciferol活化7-脱氢胆甾醇胆骨化醇(+)-维生素 D37-Dehydrocholesterol activatedCalciolActivated 7-dehydrocholesterol(+)-Vitamin D3
IUPAC name
(1S)-3-{2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
IUPAC Traditional name
cholecalciferol
Registration numbers
Beilstein Number
CAS Number
MDL Number
EC Number
Properties
Safety Information
RTECS
VS2900000
German water hazard class
2
Personal Protective Equipment
Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
GHS Signal Word
Danger
GHS Precautionary statements
P260-P280-P284-P301+P310-P310
Safety Statements
28-36/37-45
European Hazard Symbols
Highly toxic (T+)UN Number
2811
GHS Hazard statements
H301-H311-H330-H372
Storage Temperature
2-8°C
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), categories 1,2,3
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
MSDS Link
RID/ADR
UN 2811 6.1/PG 2
Hazard Class
6.1
Packing Group
2
Risk Statements
24/25-26-48/25
Physical Property
Melting Point
83-86 °C(lit.)
83-86 °C
Optical Rotation
[α]20/D +109±3°, c = 2% in ethanol
Product Information
Empirical Formula (Hill Notation)
C27H44O
Purity
≥99.0% (sum of enantiomers, HPLC)
Molecule Details
Other Notes
Review: Vitamin D: Recent advances1
Unit Definition
1 U corresponds to 1 international U according to commentary-DAB, 8th issue, 38 (1981)
Biochem/physiol Actions
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
Review: Vitamin D: Recent advances1
Unit Definition
1 U corresponds to 1 international U according to commentary-DAB, 8th issue, 38 (1981)
Biochem/physiol Actions
Vitamin D acts through a receptor that is a member of the ligand-dependent transcription factor superfamily. Modulates the proliferation and differentiation of both normal and cancer cells. Has antiproliferative and antimetastatic effects on breast, colon, and prostate cancer cells. Activated vitamin D receptors in intestine and bone maintain calcium absorbance and homeostasis.
Molecular Spectra
No Data Available
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References
No Data Available
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