Substance
ID:357764
Names and Identifiers
Synonyms
Creatineα-甲胍乙酸N-胺肉胺酸肌酸N-Amidinosarcosine(α-Methylguanido)acetic acid
IUPAC Traditional name
creatine
IUPAC name
2-(1-methylcarbamimidamido)acetic acid
Properties
Safety Information
MSDS Link
Risk Statements
36/37/38
GHS Pictograms
Acute toxicity (oral, dermal, inhalation), category 4
Skin irritation, category 2
Eye irritation, category 2
Skin sensitisation, category 1
Specific Target Organ Toxicity – Single exposure, category 3
GHS Precautionary statements
P261-P305+P351+P338
GHS Hazard statements
H315-H319-H335
European Hazard Symbols
Irritant (Xi)GHS Signal Word
Warning
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
26-36
German water hazard class
3
Product Information
Impurities
≤0.5% water
Purity
≥99.0% (NT)
Linear Formula
H2NC(=NH)N(CH3)CH2CO2H
Physical Property
Melting Point
~295 °C (dec.)
Molecule Details
Other Notes
Identification of creatine as a cofactor of thiamine-diphosphate kinase1
Biochem/physiol Actions
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.
Identification of creatine as a cofactor of thiamine-diphosphate kinase1
Biochem/physiol Actions
Creatine is a nitrogenous compound that acts as a high-energy reservoir for the rapid regeneration of ATP. Approximately 95% of creatine is found in skeletal muscle, primarily as phosphocreatine. Creatine can be acquired through dietary consumption or formed from L-arginine, glycine, and L-methionine in a multi-step reaction that occurs in the kidneys and liver. Creatine is then transported to muscle tissue. Creatine supplementation is used for the enhancement of sports performance, primarily by increasing muscle mass. Creatine is also being investigated as a treatment of neuromuscular diseases, where it may aid in neuroprotection and by improving the cellular bioenergetic state.
Molecular Spectra
No Data Available
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References
No Data Available
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