Substance

ID:357487

Names and Identifiers
IUPAC name
4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-chromen-2-one
IUPAC Traditional name
warfarin
Synonyms
Warfarin™4-羟基-3-(3-氧代-1-苯基丁基)-2H-1-苯并吡喃-2-酮华法林™杀鼠灵钠Coumafene4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin
Registration numbers
CAS Number
EC Number
Beilstein Number
MDL Number
PubChem SID
Properties
Safety Information
MSDS Link
RID/ADR
UN 2811 6.1/PG 1
Hazard Class
6.1
UN Number
2811
European Hazard Symbols
Toxic Toxic (T)
GHS Precautionary statements
P201-P273-P308+P313
Safety Statements
53-45-61
Packing Group
1
GHS Signal Word
Danger
GHS Hazard statements
H360D-H372-H412
Risk Statements
61-48/25-52/53
GHS Pictograms
GHS08
Respiratory sensitization, category 1
Germ cell mutagenicity, categories 1A,1B,2
Carcinogenicity, categories 1A,1B,2
Reproductive toxicity, categories 1A,1B,2
Specific Target Organ Toxicity – Single exposure, categories 1,2
Specific Target Organ Toxicity – Repeated exposure, categories 1,2
Aspiration Hazard, category 1
RTECS
GN4550000
German water hazard class
3
Product Information
Grade
PESTANAL®, analytical standard
Empirical Formula (Hill Notation)
C19H16O4
Physical Property
Melting Point
162-164 °C(lit.)
Molecule Details
Caution
Restricted to professional users. Attention - Avoid exposure - obtain special instructions before use.
Application
Warfarin is an anticoagulant commonly used in the prevention of thrombosis and thromboembolism. Its use is studied in stroke and pulmonary fibrosis patients among many others. It is used to study potential risks and interactions with other drugs and food1.
Biochem/physiol Actions
Warfarin consists of a racemic mixture of two active enantiomers, R- and S- forms. Warfarin is slower-acting than the common anticoagulant heparin. Warfarin inhibits the vitamin K-dependent synthesis of biologically active forms of the calcium-dependent clotting factors II, VII, IX and X. It inhibits regulatory factors protein C, protein S, and protein Z2.
Legal Information
PESTANAL is a registered trademark of Sigma-Aldrich Laborchemikalien GmbH
Warfarin is a trademark of Wisconsin Alumni Research Foundation
Molecular Spectra
No Data Available
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References
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